Jesse Vrecenak

Jesse D. Vrecenak, MD

  • Assistant Professor of Surgery

Medical School

MD, University of Pennsylvania School of Medicine, Philadelphia, Pa., 2007

Post Doctoral Education

General Surgery Resident, Hospital of the University of Pennsylvania, Philadelphia, Pa., 2007-2015

General Surgery Research Fellow, Children’s Hospital of Philadelphia, 2010-2013

General Surgery Fellow, Children’s Hospital of Philadelphia, 2015-2017

Board Certifications

Surgery – Certified

Clinical Interests

Fetal consultation and surgery, including EXIT delivery and in utero interventions

Surgical treatment of congenital diaphragmatic hernia, congenital lung lesions (CPAM/BPS), intestinal atresias, gastroschisis, omphalocele

Minimally invasive surgery, including hernia repair and surgical treatment of reflux

General pediatric surgery

Research Interests

Fetal biology/immunology and in utero cellular therapies

Hospital Affiliations

St. Louis Children's Hospital

Patients Seen At

St. Louis Children’s Hospital
One Children’s Place, 2nd floor Suite A
St. Louis, MO 63110

(314) 454-6022

Selected Publications

Partridge EA, Davey MG, Hornick MA, McGovern PE, Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 May 23;8:15794. doi: 10.1038/ncomms15794. PMID: 28534492

Antiel RM, Halpern SD, Stevens EM, Vrecenak JD, Patterson CA, Tchume-Johnson T, Smith-Whitley K, Peranteau WH, Flake AW, Barakat LP. Acceptability of In Utero Hematopoietic Cell Transplantation for Sickle Cell Disease. Med Decis Making. 2017 May 1:272989X17707214. doi: 10.1177/0272989X17707214. [Epub ahead of print] PMID: 28490230

Partridge EA, Davey MG, Hornick MA, McGovern PE, Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 Apr 25;8:15112. doi: 10.1038/ncomms15112. PMID: 28440792

Kim AG, Vrecenak JD, Boelig MM, Eissenberg L, Rettig MP, Riley JS, Holt MS, Conner MA, Loukogeorgakis SP, Li H, DiPersio JF, Flake AW, Peranteau WH. Enhanced in utero allogeneic engraftment in mice after mobilizing fetal HSCs by α4β1/7 inhibition. Blood. 2016 Nov 17;128(20):2457-2461. Epub 2016 Sep 20. PMID: 27650329

Vrecenak JD, Howell LJ, Khalek N, Moldenhauer JS, Johnson MP, Coleman BG, Victoria T, Hedrick HL, Peranteau WH, Flake AW, Adzick NS. Outcomes of prenatally diagnosed lung lesions in multigestational pregnancies. Fetal Diagn Ther. 2014;36(4):312-9. doi: 10.1159/000358325. Epub 2014 Nov 5. PMID: 25378348

Vrecenak JD, Pearson EG, Santore MT, Todorow CA, Li H, Radu A, Bhatti T, Peranteau WH, Johnson MP, Flake AW. Stable long-term mixed chimerism achieved in a canine model of allogeneic in utero hematopoietic cell transplantation. Blood. 2014 Sep 18;124(12):1987-95. doi: 10.1182/blood-2013-11-537571. Epub 2014 May 28. PMID: 24869940

Vrecenak JD, Mattei P. Fast-track management is safe and effective after bowel resection in children with Crohn's disease. J Pediatr Surg. 2014 Jan;49(1):99-102; discussion 102-3. doi: 10.1016/j.jpedsurg.2013.09.038. Epub 2013 Oct 5. PMID: 24439590

Vrecenak JD, Flake AW. Fetal surgical intervention: progress and perspectives. Pediatr Surg Int. 2013 May;29(5):407-17. doi: 10.1007/s00383-013-3304-x. Epub 2013 Apr 4. Review. PMID: 23552956

Vrecenak JD, Flake AW. In utero hematopoietic cell transplantation--recent progress and the potential for clinical application. Cytotherapy. 2013 May;15(5):525-35. doi: 10.1016/j.jcyt.2013.01.003. Epub 2013 Feb 14. Review. PMID: 23415921

Roybal JL, Laje P, Vrecenak JD, Flake AW. Use of manipulated stem cells for prenatal therapy. Methods Mol Biol. 2012;891:169-81. doi: 10.1007/978-1-61779-873-3_8.  PMID: 22648772

Chapters

Vrecenak JD, Flake AW. Fetal Surgery, Diagnosis, and Intervention. In: Ziegler MM, Azizkhan RG, Gauderer MWL (eds.). Operative Pediatric Surgery 2e. New York: McGraw Hill, New York.

Vrecenak JD, Nance M. Surgery. In: Shah SS, Zaoutis LB,  Catallozzi M, Frank G (eds.). Philadelphia Guide to Inpatient Pediatrics 2e. New York: McGraw Hill, New York.

Vrecenak JD, Nance M. Pediatric Surgery. In: Porrett, PM, Drebin, JA, Atluri, P, Karakousis, GC, Roses RE (eds.).  The Surgical Review – an Integrated Basic and Clinical Science Study Guide. 4th ed.  Philadelphia: LWW.